Recombinant EGFR (Matuzumab Biosimilar) 抗体
This anti-EGFR (Matuzumab Biosimilar) antibody is a Humanized 单克隆 antibody detecting EGFR (Matuzumab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant EGFR (Matuzumab Biosimilar) 抗体 (ABIN7795112)
抗原
EGFR (Matuzumab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
Humanized
克隆类型
单克隆
标记
This EGFR (Matuzumab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Matuzumab Biosimilar, EGFR Monoclonal Antibody
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产品特性
- Matuzumab Biosimilar uses the same protein sequences as the therapeutic antibody matuzumab. Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival. Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and blocking receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation. Matuzumab (EMD-72000) is a humanized IgG1 MAb that not only binds with high specificity and affinity to EGFR, but also modulates antibody-dependent cellular cytotoxicity (ADCC).
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human EGFR
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anti-EGFR (Matuzumab Biosimilar) (Extracellular Domain) antibody
适用: 人 ELISA, FACS, Anta, BR, IF, WB 宿主: Human Monoclonal unconjugated Recombinant Antibody
anti-EGFR (Matuzumab Biosimilar) (Extracellular Domain) antibody适用: 人 ELISA, FACS, Anta, BR, IF, WB 宿主: 兔 Chimeric unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- EGFR (Matuzumab Biosimilar)
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别名
- Matuzumab Biosimilar
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物质类
- Biosimilar
抗原
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